MDCG publishes Q & A on the MDR regarding clinical investigation

The Medical Device Coordination Group (MDCG) has published a Q & A on the Medical Devices Regulation (EU) 2017/745/ (MDR) regarding clinical investigation.

The document MDCG 2021-6 is entitled ‘Regulation (EU) 2017/745 – Questions & Answers regarding clinical investigation’.

Who is the document for?

It is intended for sponsors of clinical investigations of medical devices conducted within the scope of the Regulation (EU) 2017/745 (MDR).

About the questions in the document

The 19 page document has 28 Q & As. The document may be supplemented in due course with further questions and answers.

The questions in the document are split under the following headings:

  • General questions
  • Modifications to clinical investigations
  • Timeline considerations for clinical investigations
  • Clinical investigation reports
  • Arrangements for the transitional period

The first five questions in the document are:

  1. What are the general differences and improvements related to clinicalinvestigations under the new Regulation (EU) 2017/745 (MDR) as compared to the Directives 93/42/EEC and 90/385/EEC?
  2. What is a clinical investigation?
  3. What is the difference between the performance, clinical performance and clinical benefit?
  4. Which regulatory pathway shall a sponsor follow in order to conduct a clinical investigation to collect clinical data that will be used to support the conformity assessment procedure of the investigated medical device?
  5. What is a pilot clinical investigation?

This document should prove to be quite useful for anyone wanting to get a basic and clear understanding on the subject of clinical investigations with medical devices.

Source: Europa website.